IGF1-LR3 (Insulin-like Growth Factor 1 Long Arg3) is a synthetic, modified form of IGF-1 consisting of 83 amino acids. The Arg3 substitution at position 3 and a 13-amino-acid N-terminal extension significantly reduce binding to IGF-binding proteins, resulting in enhanced bioavailability and a longer half-life compared to native IGF-1. Widely used in cell culture and in vivo research models studying proliferation, differentiation, and metabolic signaling. Provided as a high-purity lyophilized research compound.

Product Specifications

• Amount per vial: 1mg
• Form: Lyophilized powder
• Molecular Weight: 9117.5 g/mol
• Solubility: Soluble in 10 mM HCl or 0.1 M acetic acid

Amino Acid Sequence

Handling & Storage

• Store lyophilized at -20°C or below. Reconstitute in sterile acidified water (10 mM HCl) or 0.1 M acetic acid. Aliquot reconstituted solution and store at -80°C. Avoid repeated freeze-thaw cycles.
• For trained personnel handling research chemicals in an appropriate lab setting.
• Use proper PPE and standard laboratory safety practices when handling.